Eat More, Weigh Less, Live Longer
Clever genetic detective work may have found out the reason why a near-starvation diet prolongs the life of many animals.
Ronald Kahn at Harvard Medical School in Boston, US, and his colleagues have been able to extend the lifespan (寿命) of mice by 18 per cent by blocking the rodent’s (啮齿动物) increase of fat in specific cells. This suggests that thinness—and not necessarily diet—promotes long life in "calorie (热量卡) restricted" animals.
"It’s very coal work," says aging researcher Cynthia Kenyon of the University of California, San Francisco. "These mice eat all they want, lose weight and live longer. It’s like heaven."
Calorie restriction .dramatically extends the lifespan of organisms as different as worms and rodents. Whether this works in humans is still unknown, partly because few people are willing to submit to such a strict diet.
But man
A. offering them less food.
B. giving them a balanced diet.
C. disrupting the specific genes in their fat cells.
D. preventing them growing larger.
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