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Eat More, Weigh Less, Live Longer
Clever genetic detective work may have found out the reason why a near starvation diet prolongs the life of many animals.
Ronald Kahn at Harvard Medical School in Boston, U.S., and his colleagues have been able to extend the lifespan of mice by 18 per cent by blocking the rodent’s increase of fat in specific cells. This suggests that thinness and hot necessarily diet promotes long life in "calorie restricted" animals.
"It’s very cool work." says aging researcher Cynthia Kenyon of the University of California, San Francisco. "These mice eat all they want, lose weight and live longer. It’s like heaven."
Calorie restriction dramatically extends the lifespan of organisms as different as worms and rodents. Whether this works in humans is still unknown, partly because few people are willing to submit to such a strict diet.
But many researchers hope they will be able to trigger the same effec
A. humans, worms and rodents are different.
B. most people are not willing to be put on a strict diet.
C. the effect is not known.
D. genetic changes in tissues can not be performed on humans.