[不定项选择题]共用题干
Cancer Drug Trials Often Halted Early
An increasing number of clinical trials for new cancer treatments are being halted before the risks and benefits have been fully evaluated,say Italian researchers,who warn that this growing trend could put patients at risk of harm from new therapies rushed into use.
The researchers looked at 25 randomized,controlled clinical trials that were stopped ear-ly because the treatments had started to show benefit to patients.
“When we analyzed 25 trials over a 10-year period between 1997 and 2007,we found a consistent increase in prematurely stopped trials一more than 50 percent were stopped within the last three years,”study co-author Giovanni Apolone said at a news conference Tuesday.
Of 14 trials halted early and published between 2005 and 2007,the researchers found that 11(79 percent)of them were used to support drug approval applications submitted to the European Medicines Agency and the U.S.Food and Drug Administration.
“This suggests a strong commercial component in stopping trials prematurely.In fact, this strategy could guarantee quicker access to the market for companies.On the other hand, a quicker clinical drug development may lead to an ‘immature’benefit/risk balance of new drugs,”Apolone said.
He and his colleagues“are aware that trials stopped early because they are showing ben-efit may result in identification of promising new treatments for patients.However,findings obtained following this strategy should be considered to be preliminary results that require subsequent confirmation.”
It can take several years for the long-term benefits or harmful side effects of a new treat-ment to become apparent, Apolone noted, but the average duration(持续时间)of the 25 studies he and his colleagues analyzed was 30 months,with a range from 12 to 64 months.
They also found that at the time five of the studies were stopped,they'd enrolled less than 40 percent of the total number of patients planned for final analysis.
“Clinical trials need to stop early for superior benefit whenever there's proof beyond rea- sonable doubt that the new treatment really is superior.That would be an ethical obligation,” Stuart Pocock,a professor of medical statistics at the London School of Hygiene and Tropi-cal Medicine in the United Kingdom,said at the news conference.“However,too many trials are stopped early claiming efficacy(功效)without strong evidence being available.”
Some of the trials were too short to show their long-term effects.
A.Right
B.Wrong
C.Not mentioned
[填空题]
· Read the article below about money management in Britain.
· For each question 31-40.write one word in CAPITAL LETTER on
your Answer Sheet.
Younger people are more likely to talk about their money issues than their
elder counterparts,it has been revealed.Saga Personal Finance has found that 14
percent of over-50s are happy to talk about their finances ln{{U}} (31)
{{/U}},compared to 21 percent of under.50s.People{{U}} (32)
{{/U}}.claimed they are unwilling to discuss money openly said they believe
those matters should stay private(50 percent)and a tenth explained it was{{U}}
(33) {{/U}} they were embarrassed about their financial
situation.Around half of the under-50s said they were happy to{{U}} (34)
{{/U}}.money with their friends,whereas this fell to 30 percent among the
older group.It was also revealed that 71 percent of Brits in a relationship have
a separate current{{U}} (35) {{/U}},explaining that they want to keep
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[单项选择]广告费按不超过营业收入()的比例据实列支。
A. 1%
B. 1.5%
C. 2%
D. 2.5%
[判断题]抢劫罪侵犯的客体是财产所有权和人身权。
正确 错误
一、单选题(共40题,每题1.0分,每道题只有一个正确答案!)
A.正确
B.错误
[单项选择]钢筋混凝土梁即将裂缝时,受拉钢筋的应力σs与配筋率ρ的关系是()。
A. ρ增大,σs减小
B. 减小,σs 增大
C. 关系不大
[多项选择]在Excel 2013电子表格中,可以进行计算的是()。
A. 数值
B. 文本
C. 公式
D. 日期
[多项选择]客户选择第三方物流企业注重的因素有()
A. 物流企业的行业与运营经验
B. 物流企业的资产规模
C. 物流企业的服务价格
D. 物流企业的品牌声誉
E. 物流企业的网络覆盖率
[判断题]利用高空作业车、带电作业车、叉车、高处作业平台等进行高处作业,高处作业平台应处于稳定状态,需要移动车辆时,作业平台上不准载人。
A.正确
B.错误
[多选题]下列关于人民币对公一户通主账户基本规则的表述,正确的是
A.主账户体现子账户之间的交易明细
B.通过主账户购买的支付结算凭证,可用于其下设的所有子账户
C.通过主账户签约或解约金融服务的,其下设的所有子账户视同签约或解约相应金融服务。
[单选题]厦门地铁2号线电客车救援模式下,列车最高限速为( )km/h。
A.30
B.45
C.55
D.60
[单选题]锅炉是一种燃烧化石燃料以产生( )的热力设备。
A.煤气
B.蒸汽
C.烟气
D.石油
[单项选择]用美容放大镜观察毛细血管扩张的皮肤,毛孔较细,皮肤毛细血管()。
A. 十分明显
B. 不明显
C. 看不出
D. 较少
[单选题]《山东省安全生产条例》规定,禁止生产经营单位接受( )和其他未成年人从事接触危险物品的劳动或者其他危险性劳动。
A.中小学生
B.实习学生
C.女职工
D.劳务派遣人员
[判断题]焊接时可以多台焊机共用一个电源开关
A.正确
B.错误
[单项选择]建立一个新的标准模块,应该选择哪个菜单下的“添加模块”命令
A. “工程”菜单
B. “文件”菜单
C. “工具”菜单
D. “编辑”菜单
[填空题]Objects which fall freely in a vacuum have same rate of speed regardless of differences in size and weight.
[多项选择]渝城有限责任公司因章程规定的营业期限届满而解散,成立了清算组。清算组在清算期间实施的下列行为哪些是错误的
A. 为抵偿甲公司的债务而承揽了甲公司的一项工程
B. 以清算组为原告起诉一债务人
C. 留足偿债资金后将公司财产按比例分配给各股东
D. 从公司财产中优先支付清偿费用
[多选题]《铁路旅客运输服务质量规范》(铁总运〔2016〕247号)规定:商品柜、储藏室、蔬菜柜、吧台橱柜(陈列柜)加锁,不放置私人物品;()定位放置,不占用通道和旅客使用空间。
A.售货车
B.商品
C.餐料
D.售饭车
[单项选择](By) the end of the nineteenth century, organic chemistry had (develop) new (methods) for the (synthesis) of dyes, perfumes, explosives, and medicines.()
A. By
B. develop
C. methods
D. synthesis
[填空题]最常用的人-机接口器件有()、()和()。
[单选题]《银行业金融机构从业人员职业操守指引》 规定,银行业金融 机构从业人员应遵循公平竞争,恪守( )原则。
A.客户至上
B.诚实守信
C.客户自愿
D.公开公正
[多选题]被害人王某被张某打伤,关于本案中的伤情鉴定,以下说法中正确的是( )。
A.鉴定人故意作虚假鉴定的,应当承担法律责任
B.犯罪嫌疑人张某作精神病鉴定的期间不计入办案期限
C.侦查机关应当将用作证据的鉴定意见告知张某,但无需告知王某
D.侦查机关应当将用作证据的鉴定意见告知张某和王某
[单选题]在坑沟边使用机械挖土时,应( ),确保作业安全。
A.计算机械压力
B.检测土层变化
C.设置专人监护
D.计算支撑强度
[简答题]甲企业位于大连,在上海有一个分支机构乙。2002年1月,乙与位于上海的丙企业在上海签订一个买卖合同。合同中约定:丙向乙购买货物,买卖合同的价值为50万元;丙先付15。万元的定金,于2002年5月底前丙去大连甲企业处提货,丙见货后3日内付清货款;逾期违约金为标的额的5%。2002年1月21日,丙付了15万元的定金,于2002年5月1日去大连甲处提货时被告知货未准备好,10日内一定交货。5月12日甲再次以未准备好为由推托。据了解得知,甲企业3月初才开始准备生产这批货,丙要想在5月拿到货是不可能的,于是丙向乙提出解除合同。
请就上述内容做以下的分析:
(1)因合同引起的纠纷可以通过哪些途径解决
(2)乙与丙的纠纷能否不诉讼为什么
(3)如果诉讼,诉讼管辖的人民法院是谁
(4)丙提出解除合同有没有法律依据
(5)如果乙的财产不足以承担丙的违约责任怎么办为什么
(6)如果丙未造成实际损失,丙可以向乙要求承担多少违约责任
[判断题]关于氨泵的操作,原则上是先开机,后开泵,先开风机,后供液。
A.正确
B.错误
[判断题]高层建筑发生火灾,开通广播系统应先通知着火楼层和受烟火威胁的上层人员。
A.正确
B.错误
[单选题]下列哪项是肝硬化的典型病理改变
A.纤维组织增生
B.肝细胞变性坏死
C.不同程度的炎性细胞浸润
D.再生结节及假小叶形成
[单选题] 我国第一个五年计划完成于( )。
A.大跃进时期
B.全面进行社会主义建设时期
C.社会主义改造时期
D.国民经济大调整时期
[单选题]邓小平在《永远记取党的斗争经验和教训》(1951年6月25日提到:马列主义是放之四海而皆准的普遍真理,假若不与各国实际结合起来就会变成______。
A.教条主义
B.机会主义
C.形式主义
D.本本主义
[多项选择]企业交纳的下列税金中,应计入当期损益的有( )。
A. 企业按规定计算缴纳的车船税
B. 企业购置的免税车辆因改制后用途发生变化而按规定补交的车辆购置税
C. 企业自行建造厂房而交纳的耕地占用税
D. 运输企业提供运输劳务取得收入而交纳的营业税
E. 企业购入商品房按规定交纳的契税
[判断题]纤维胃镜目视诊断为胃癌而活检未发现癌细胞可排除胃癌。( )
内科学
A.正确
B.错误
[单选题]在多云天气下,光线散射、柔和而均匀,此时最适合于拍摄( )景象。:
A.人像
B.风景
C.建筑
D.运动中的物品
[判断题]连铸铸坯凝固时,除铸坯两端头尾外,铸坯沿长度方向上组织均匀,结构致密。( )
A.正确
B.错误
[单选题] 示波器电子枪灯丝的作用是( ??)。
A.降温阳极
B.降温阴极
C.加热阳极
D.加热阴极