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[单项选择]What time is it now
A. He is not interested in going.
B. He wants to go with them.
C. He will invite his friends.

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[单选题] 客户损坏补打存款资信证明时,应归还已损坏存款资信证明原件,存款人只能补打(  )名下的个人存款证明
A.本人
B.父母
C.子女
D.配偶
[不定项选择题]共用题干 Cancer Drug Trials Often Halted Early
An increasing number of clinical trials for new cancer treatments are being halted before the risks and benefits have been fully evaluated,say Italian researchers,who warn that this growing trend could put patients at risk of harm from new therapies rushed into use.
The researchers looked at 25 randomized,controlled clinical trials that were stopped ear-ly because the treatments had started to show benefit to patients.
“When we analyzed 25 trials over a 10-year period between 1997 and 2007,we found a consistent increase in prematurely stopped trials一more than 50 percent were stopped within the last three years,”study co-author Giovanni Apolone said at a news conference Tuesday.
Of 14 trials halted early and published between 2005 and 2007,the researchers found that 11(79 percent)of them were used to support drug approval applications submitted to the European Medicines Agency and the U.S.Food and Drug Administration.
“This suggests a strong commercial component in stopping trials prematurely.In fact, this strategy could guarantee quicker access to the market for companies.On the other hand, a quicker clinical drug development may lead to an ‘immature’benefit/risk balance of new drugs,”Apolone said.
He and his colleagues“are aware that trials stopped early because they are showing ben-efit may result in identification of promising new treatments for patients.However,findings obtained following this strategy should be considered to be preliminary results that require subsequent confirmation.”
It can take several years for the long-term benefits or harmful side effects of a new treat-ment to become apparent, Apolone noted, but the average duration(持续时间)of the 25 studies he and his colleagues analyzed was 30 months,with a range from 12 to 64 months.
They also found that at the time five of the studies were stopped,they'd enrolled less than 40 percent of the total number of patients planned for final analysis.
“Clinical trials need to stop early for superior benefit whenever there's proof beyond rea- sonable doubt that the new treatment really is superior.That would be an ethical obligation,” Stuart Pocock,a professor of medical statistics at the London School of Hygiene and Tropi-cal Medicine in the United Kingdom,said at the news conference.“However,too many trials are stopped early claiming efficacy(功效)without strong evidence being available.” Stuart Pocock believed that in no case should clinical trials stop early.
A.Right
B.Wrong
C.Not mentioned
[单项选择]


A. have
B. possess
C. need
D. lack
[判断题]膨胀压缩机超速,会造成轴承过热。( )
A.正确
B.错误
[多选题]焊条选择的原则( )。
A.经济性原则
B.等强度原则
C.同等性能原则
D.等条件原则
[单选题]自由时差是指______。( )
A.在不影响总工期的条件下,可以延误的最长时间
B.在不影响紧后工作最早开始时间的条件下,允许延误的最长时间
C.完咸全部工作的时间
D.完成工作时间
[单选题]由消费者收入或偏好等因素的变化引起需求的相应变化,这种变化表现为( )。
A.需求曲线上点的变动
B.需求曲线的位移
C.供给曲线的位移
D.需求函数不变
[单项选择]在软件开发中,应从哪个阶段开始准备初步的用户手册
A. 编码
B. 测试
C. 总体设计
D. 需求分析
[多项选择]关于糖尿病的转诊原则的说法正确的是()
A. 可疑糖尿病患者诊断不能明确者
B. 各型糖尿病患者口服降糖药无效者
C. 出现并发症或伴发症者
D. 近期血糖波动较大,调整剂量无效者
E. 患者处于应急状态者
[单选题] SIV的数据接口位于哪节车下的箱体?(1.0分)
A.A、1车和6车
B.B、2车和5车
C.C、3车和4车
D.D.、全部车厢都有
[单项选择]最常用的皮肤缝合方法是( )
A. 单纯间断缝合
B. 皮内缝合
C. 单纯连续缝合
D. 内“8”字缝合
E. 外“8”字缝合
[判断题]工业一、二类建筑物、构筑物,其冲击接地电阻应不大于 10 。工业三类及民用一、二类建筑物、构筑物,其冲击接地电阻应不大于 30 。( )
A.正确
B.错误
[多项选择]依法行政原则的具体要求是()
[单选题]气体灭火系统,使用中应当注意防毒、防冻伤。( )
A.正确
B.错误
[单项选择]校园的整体规划及其建筑风格应反映学校内在的文化特色,它主要反映的文化形态是()
A. 校园物质文化;
B. 校园行为文化;
C. 校园制度文化;
D. 校园精神文化
[判断题]标准酒度是指在20℃条件下,每100毫升酒液中含有多少毫升的酒精。
[填空题]紧张性头痛一般不会因疼痛严重而影响_______,患者整天头痛,但一天内可逐渐增强和逐渐减轻。
[判断题]在叉车任何场地驾驶操过程中均不得中途熄火出线随意停车。
[多项选择]下列各科目,年末应无余额的是( )。
A. 管理费用
B. 所得税费用
C. 其他业务收入
D. 长期待摊费用
[多选题]铁路工务、电务、车务、供电等部门因作业需要在防护栅栏中设置作业门时,下列要求中正确的是( )。
A.作业进出防护栅栏门时应专人看守。
B.由使用单位提出申请报铁路局栅栏设备管理部门批准,站区内还需经车务部门批准。
C.经与栅栏设备管理单位和属地铁路公安部门办理书面手续后方可设置。
D.铁路工作人员专用通道、作业门应有警示标识。
[单选题]( )是指公司各层级单位为完成某项综合性任务设立的跨部门、跨单位的组织协调机构。
A.非常设机构
B.常设机构
C.普通机构
D.非普通机构
[单选题]有关精益生产正确的说法是()。
A.精益生产是QR战略在生产领域的延续
B.精益生产是在日本丰田JIT生产的基础上提出来的新的生产方式
C.精益生产追求的是对定制化需求的快速反应
D.精益生产是大规模定制的另一种说法
[单选题]安全放散阀校验周期为( )。
A. 1年
B. 2年
C. 3年
[单项选择]女,25岁。心悸,气促,下肢水肿4年。望诊心脏负性心尖搏动,已排除粘连性心包炎,问可发现下列何项体征()。
A. 叩诊心脏呈靴型增大
B. 心前区隆起
C. 心音遥远
D. 胸骨左缘扪及收缩期震颤
E. 交替脉
[单项选择]患者女,45岁,因“渐进性四肢无力3个月”来诊。不伴肢体麻木和疼痛,无病态疲劳。糖尿病5年,控制较好。查体:脑神经未见异常,四肢肌力Ⅳ级,腱反射消失,病理反射未引出,踝以下振动觉减退,余感觉正常。治疗首选药物为()
A. B族维生素
B. 利鲁唑
C. 降糖药
D. 糖皮质激素
E. 丙种球蛋白
[单项选择]在一恒压的电路中,电阻R增大,电流随之()
A. 减小
B. 增大
C. 不变
D. 不一定
[单项选择]被称为“读万卷书,行万里路的大学者”,并开清代考据学之先河的思想家是()
A. 李贽
B. 黄宗羲
C. 顾炎武
D. 王夫之
[单选题]清筛机、物料车、配砟车在作业中应注意()等障碍物,以防刮碰。
A.接触网支柱
B.信号机
C.接触网支柱、信号机
D.电务设备
[单项选择]头孢克洛( )。
A. 结构中含有氧哌嗪环
B. 结构中含有氰基
C. 结构中含有噻吩环
D. 结构中含有甲氧肟
E. 结构中含有氯
[判断题]活动排序就是确定各活动之间完成的先后顺序
[单选题]中暑时最容易发生肌肉痉挛的是( )
A.腹直肌
B.腓肠肌
C.胸大肌
D.咀嚼肌
E.面肌

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